Peaccel, a Bio-IT company that provides predictive solutions for protein engineering services, signed a Memorandum of Understanding (MoU) with Polyclone Bioservices to utilise Polyclone’s in silico enzyme engineering framework (eEF) to strengthen its protein engineering services. Collaborations under this MoU are focused on offering specifically enzyme engineering services to optimise enzymes for better activity, stability and specificity under process conditions.
“Peaccel’s vision is to command a leading commercial presence in predictive solutions for directed molecular evolution and protein engineering through its unique sets of algorithms and know how. Polyclone’s outstanding technology for enzyme engineering services is perfectly complementary to our services. We believe our partnership with Polyclone is a great opportunity to leverage our respective commercial presence in the fast growing enzyme engineering industry,” said Dr Frédéric Cadet, Vice President – Business Development, Peaccel.
“Polyclone’s in-depth expertise in molecular modeling and simulation complements perfectly our own expertise on semi-rational design and rational screening. We have good traction with their scientists. Altogether, this provides us the opportunity to offer a fully integrated solution to the enzyme engineering market” said Dr Bernard Offmann, VP – Research for Peaccel.
“Our enzyme engineering framework, eEF is a smart integration of proprietary algorithms and processes for high throughput and high confidence predictions of enzyme and protein modifications for desired properties. The solution integrates computational library design, directed evolution and statistical modelling of sequence–function relationships while considering the intermediary stages of enzyme-substrate interaction to achieve its goals,” said Naveen Kulkarni, Chief Executive Officer, Polyclone. He added, “With the recognition of importance of molecular dynamics (MD) in this year’s Nobel prize for chemistry, it has further affirmed our approach, and the extensive experience that Peaccel brings to this collaboration, provides unparalleled advantage to our customers in solving highly complex enzyme productivity issues and we hope to contribute to better financial outcomes combining this with a greener objective.”
EP News Bureau – Mumbai