USFDA issues CRL for proposed biosimilar Insulin-R: Biocon

The US Food and Drug Administration (USFDA) issues a Complete Response Letter (CRL) to convey to a company that its initial review of an application is complete and it cannot approve the application in its present form

Biocon recently said the US health regulator has issued a complete response letter for Biocon Biologics’ application for Insulin-R, a proposed biosimilar for diabetes treatment.

The United States Food and Drug Administration (USFDA) issues a Complete Response Letter (CRL) to convey to a company that its initial review of an application is complete and it cannot approve the application in its present form.

“The USFDA has issued a CRL for the Biologics Licence Application (BLA) for the Insulin-R product filed by Biocon Biologics,” Biocon said in a regulatory filing.

The CRL cites additional data required in the BLA submission and an expectation of satisfactory implementation of a Corrective and Preventive Action Plan (CAPA) pertaining to the pre-approval inspection of the company’s Bengaluru facilities in August last year, it added.

“We are in the process of comprehensively addressing the CRL,” a Biocon Biologics spokesperson noted.

Edits by EP News Bureau

BioconComplete Response letterdiabetes treatmentInsulin R: biosimilarUSFDA
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