Roche’s Alzheimer’s drug fails to meet goal in long awaited trial
The Swiss drugmaker conducted two identically designed studies, each with about 1,000 participants, who were examined and queried…
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Research
Indian drug 2DG can reduce heart damage by coronavirus, find US researchers
Their findings, based on research with fruit flies and mouse heart cells, were published in 'Communications Biology,' a 'Nature'…
US government to test Pfizer’s Paxlovid for long COVID
The Duke Clinical Research Institute is supervising the study, which is scheduled to start on 1st January
AstraZeneca drug fails one main goal in study of chronic immune disease
Despite the setback from the trial, AstraZeneca said it would continue to analyse the complete data set, which included 210…
Three-dose hepatitis-B vaccine regimen protects people with HIV: NIH
Finding is part of an ongoing clinical trial
GSK says key trial data shows its RSV vaccine is ‘truly exceptional’
The trial, which involved roughly 25,000 adults aged 60 years and more, tested a single dose of the experimental vaccine against a…
Relmada’s depression drug fails to meet late-stage study goal
Relmada will continue to study REL-1017, its lead treatment, as an adjuntive or in combination with other depression drugs
Antibacterial Resistance Leadership Group (ARLG) begins clinical trial of phage therapy for cystic…
The trial is evaluating whether the bacteriophage, or “phage,” therapy is safe and able to reduce the amount of bacteria in the…
Prenatal steroid treatment may improve survival, reduce complications for pre-term infants: Study
The study authors concluded that their results provide strong evidence to support giving ante-natal steroid therapy to pregnant…
Promising MND drug helps slow disease progression and benefits patients physically
Patients on the trial reported better patient mobility and lung function after 12 months
Merck to initiate new clinical programme with lower dose of daily oral Islatravir in combination…
Phase-II study evaluating an investigational weekly oral combination treatment regimen of Islatravir and Gilead Sciences’…
Pfizer announces positive results from phase-III study in 20-valent Pneumococcal Conjugate Vaccine…
The company intends to file for regulatory approval in the EU in the next few months
European Commission approves Roche’s Vabysmo to treat vision loss
Vabysmo is the only injectable eye medicine approved in Europe with phase-III studies supporting treatment at intervals of up to…
Sandoz announces positive results for biosimilar Denosumab
The results came soon after Sandoz confirmed acceptance of licence applications for two other proposed biosimilars
Pfizer announces positive top-line results from phase-III trial of pentavalent meningococcal vaccine…
Phase-III trial demonstrates that the investigational pentavalent meningococcal vaccine (MenABCWY) was well-tolerated with an…
Bharat Biotech seeks drug regulator’s nod for Incovacc’s phase-III study in five-18 age…
Incovacc is a recombinant replication deficient adenovirus vectored vaccine with a pre-fusion stabilised spike protein
Amgen says Lumakras cuts risk of lung cancer progression by 34 per cent
The medication is designed to target a mutated form of a gene known as KRAS that occurs in about 13 per cent of non-small cell…
US begins clinical trial to evaluate antiviral for monkeypox
The US-based National Institute of Health (NIH) to gather data on tecovirimat (TPOXX)
AI and automation in clinical trials
Manuj Vangipurapu, founder and CEO, Clinion, briefly discusses the many well-known and lesser-known uses of AI and automation in…
ZeNix trial shows effectiveness of BPaL regimen for TB can be maintained with reduced dosing of…
The results from the trial, which was led by TB Alliance, were published in the 'New England Journal of Medicine'