Biogen scraps two Alzheimer drug trials, wipes $18 billion from market value
The two halted trials were in the final stages of testing aducanumab in patients with mild cognitive impairment due to Alzheimer’s…
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Research
GSK reports positive data for experimental blood cancer drug
The DREAMM-1 study of patients with relapsed/refractory multiple myeloma confirmed the potential effectiveness of the medicine
Roche’s Tecentriq notches win in breast cancer with US approval
The FDA’s OK was based on a trial that showed the drug cocktail helped stave off the disease’s advance by a median 7.4 months,…
Large meta-analysis backs probiotic benefits in gut health
Focussed analysis of 53 Chinese clinical trials shows efficacy of probiotic formula Medilac-S as adjuvant treatment in ulcerative…
J&J’s nasal spray for depression wins FDA panel backing
The panel members echoed concerns raised by FDA staffers regarding the increased risk of sedation, dissociation and higher blood…
Gilead misses key goal in NASH liver disease trial
Analysts have projected the market for NASH treatments to reach $20 billion to $35 billion as populations with fatty diets…
Merck, Pfizer drug combo extends kidney cancer survival: Study
Merck released interim data from the trial, saying the combination reduced the risk of death by 47 per cent compared with Sutent
Effects of linoleic acid on inflammatory response depend on genes
The findings indicate that the effects of linoleic acid on the human body are largely dependent on which variant of the FADS1 gene…
Sanofi blood disorder drug wins FDA approval
The US Food and Drug Administration (FDA) said it had approved Sanofi's drug to treat a rare blood-clotting disorder in adults in…
Genetic study reveals possible new routes to treating osteoarthritis
Largest ever genetic study of osteoarthritis uncovered 52 new genetic changes linked to the disease
Amgen’s postmenopausal osteoporosis drug wins FDA panel backing
The drug, Evenity, helps reduce the risk of fracture by increasing bone formation and inhibiting break down of bone minerals
Zebrafish help unlock mystery of motor neurone disease
Trialing 1,000 drugs on mice models would take more than 10 years, however trialling 1,000 drugs on zebrafish would take only a…
Roche-AbbVie cancer drug gets accelerated FDA approval
The drug, developed in partnership with AbbVie, was approved for patients with acute myeloid leukemia
Delivering a baby increases, then lowers, risk of breast cancer: Study
Researchers found that the breast cancer risk peaks 4.6 years after a woman’s most recent birth but then begins to fall
J&J says its psoriasis drug superior to Novartis treatment: Study
Psoriasis is a chronic condition that causes an overproduction of skin cells, resulting in inflamed, red lesions or plaques, which…
Novel antibacterial drugs developed at University of Eastern Finland
In the era of increased antibiotic resistance, it is necessary to focus on developing new antibacterial agents
Novartis abandons effort for US approval of biosimilar rituximab
The decision comes after the US Food and Drug Administration (FDA) sought additional information to support the company’s…
Anesthesia in early childhood not tied to developmental problems
Young children who had surgery under general anesthesia were no more likely than their siblings who weren’t exposed to anesthesia…
Lilly says diabetes drug Trulicity reduces heart risks in trial
The company did not provide any details on the magnitude of risk reduction seen in the so-called outcomes trial
Ciprofloxacin has dramatic effects on mitochondrial genome
While they are generally well tolerated, some patients receiving fluoroquinolones develop severe health problems, among them…