Dr Rakesh Bhasin, VP and Head R&D (Formulations), Biocon Pharma | FDD Conclave 2022
In this video:
Dr Rakesh Bhasin, VP and Head R&D (Formulations), Biocon Pharma
Topic: Advancements in oral dosage forms
Key Highlights:
+ Power liquid 3D printing offers unique advantages and opportunities for the pharma industry, as recognised by FDA and other industry leaders
+ 3D printing rapidly disperses tablets dose load upto 1,000 mg and makes multiple taste masking amenable, while providing several other benefits
+ Evaluation of liquipellet involves assay, flowability, friability, PSD, SEM and dissolution study
+ Formulation of SEDDS/SMEDDS includes solubility of the drug in different oils, surfactants and co-solvents; selection of oil, surfactant and co-solvent based on the solubility of the drug and preparation of the phase diagram
+ Benefits of SEDDS liquid and solid are improved pharmacokinetic, improved pharmacodynamic, improved stability and industrial feasibility
+ Based on the understanding of the physicochemical properties of the drug, selection of right technology can increase oral bioavailability of a drug
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