Omnicron less likely to cause long COVID: UK Study

The Omicron variant of coronavirus is less likely to cause long COVID than previous variants, according to the first peer-reviewed study from the UK.

Researchers at King’s College London, using data from the ZOE COVID Symptom study app, found the odds of developing long COVID after infection were 20 per cent to 50 per cent lower during the Omicron wave in the UK compared to Delta. The figure varied depending on the patient’s age and the timing of their last vaccination.

Long COVID, which includes prolonged symptoms ranging from fatigue to ‘brain fog’, can be debilitating and continue for weeks or months. It is increasingly being recognised as a public health problem, and researchers have been racing to find out if Omicron presents as big a risk of long COVID as previously dominant variants.

The study from King’s is believed to be the first academic research to show Omicron does not present as great a risk of long COVID, but that does not mean long COVID patient numbers are dropping, the team said.

While the risk of long COVID was lower during Omicron, more people were infected, so the absolute number now suffering is higher.

It also said the risk of lingering symptoms after Omicron was lower than with Delta, but only for double-vaccinated people. It found no statistical difference for those who were triple vaccinated.

In King’s research, 4.5 per cent of the 56,003 people studied during Omicron’s peak, December 2021-March 2022, reported long COVID. That compared to 10.8 per cent of 41,361 people during the Delta wave, June-November 2021. It did not compare vaccinated and unvaccinated individuals.

The study – published in The Lancet journal – compared Delta and Omicron, revealed that previous work had shown no substantial difference in long COVID risk between other variants. More work was needed to establish why Omicron may have a lower long COVID risk, the team added.

(Edits by EP News Bureau)