US CDC publishes guidelines on monkeypox vaccine

The Jynneos vaccine, made by Bavarian Nordic, will be available for certain healthcare workers and laboratory personnel at a time when monkeypox infections has spread in Europe, US and beyond.

The vaccine was approved in the US in 2019 to prevent smallpox and monkeypox in high-risk adults aged 18 years and older.

CDC officials earlier this week said they were in the process of releasing some doses of the Jynneos vaccine for people in contact with known monkeypox patients.

Officials said there were over 100 million doses of an older smallpox vaccine called ACAM2000, made by Emergent BioSolutions, which has significant side effects.

Monkeypox is a mild viral infection that is endemic in certain parts of Africa, but the recent outbreak in countries where the virus doesn’t usually spread has raised concerns.

So far, there are about 300 confirmed or suspected cases in around 20 countries where the virus was not previously circulating. The World Health Organization (WHO) has called for quick action from countries to contain the Monkeypox spread.

The CDC said its experts’ recommendations are meant for clinical laboratory personnel performing diagnostic tests for orthopoxviruses such as smallpox and monkeypox, laboratory people doing research on the viruses and healthcare workers who administer the ACAM2000 vaccine or care for patients infected with orthopoxviruses.

The publication of the vote by the CDC’s Advisory Committee on Immunization Practices, which took place in November last year, formalises the recommendations.

Both ACAM2000 and Jynneos are available for prevention of orthopoxvirus infections among at-risk people, the CDC said yesterday.

Edits by EP News Bureau