Valedictory Address: Dr Raj Suryanarayanan, Professor and William & Mildred Peters Endowed Chair, Department of Pharmaceutics, College of Pharmacy, University of Minnesota

In this video:
Valedictory Address: Dr Raj Suryanarayanan, Professor and William & Mildred Peters Endowed Chair, Department of Pharmaceutics, College of Pharmacy, University of Minnesota

Topic: Recent advances in the solid state drug product characterization

Key Highlights:
+ Change from amorphous to crystalline form of drugs leads to a loss in bioavailability
+ If we are not careful, the amorphous drugs will convert to crystalline, and the products might have to be recalled from the market
+ About 50% of all drug molecules are administered as salts
+ Dissolution rate, bioavailability and solubility are some of the advantages of salt formation
+ Factors causing disproportionation of drugs include excipients, humidity, temperature and mechanical activation/processing parameters