Waters has launched a novel series of UltraPerformance LC (UPLC) and High Performance Liquid Chromatography (HPLC) columns for peptide mapping and proteomics as well as for the analysis and lab-scale purification of synthetic peptides. Waters ACQUITY UPLC CSH130 C18 and XSelect HPLC CSH130 C18 Columns set a new standard in the analysis and purification of peptides and for the quality of information generated by UPLC, LC and LC-MS assays.
Waters’ synthesis process is unique for its Charged Surface Hybrid (CSH) particles that imparts a low level positive charge to the surface of each particle. This CSH particle technology allows the columns to be used with a weaker acid modifier such as formic acid to deliver greater resolving power and improved method sensitivity – especially when compared to standard LC-MS methods that use MS signal-suppressing ion pairing additives such as trifluoroacetic acid (TFA). In fact, in test after test, with formic acid the CSH130 C18 Columns produce significantly better peak efficiency than all other columns at all temperatures/ flow rates.
EP News Bureau – Mumbai
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