New products include bench top Tof MS, solutions
Waters Corporation has revealed new mass spectrometers, new LC/MS instruments for pesticide residue screening and metabolite identification applications, and a new Omics Research Platform at the ASMS Conference on Mass Spectrometry and Allied Topics, the largest scientific conference dedicated to the science of mass spectrometry.
Waters has introduced two new additions to its popular line of Xevo mass spectrometers – the Xevo G2-S QTof and Xevo G2-S Tof mass spectrometers – for the first time bringing Waters proprietary StepWave ion optics technology to its benchtop quadrupole time-of-flight mass spectrometry products. StepWave is a unique, off-axis ion source technology that delivers robust, reproducible, class-leading sensitivity to mass spectrometry.
GlaxoSmithKline Pharmaceuticals is one company putting StepWave technology to good use. “Micro-sampling, either through the use of dried blood spots (DBS) or novel techniques for the separation of sub 50 microliters of plasma, is an area of innovation that GlaxoSmithKline is actively pursuing,” says Chet Bowen, an investigator with the Bioanalytical Science and Toxicokinetics PTS DMPK Department at GlaxoSmithKline Pharmaceuticals.
“In some instances we would like to use 5-10 microliters of biological matrix, therefore we need a mass spectrometer detector capable of achieving low pg/mL detection limits with minimal sample volumes which is why we chose the Waters Xevo TQ-S with StepWave technology. Coupled to an ACQUITY UltraPerformance LC System, it easily enables us to achieve these lower limits of quantification from reduced volume matrices. Additionally, this instrument combination facilitates low LLQ requirements to support our inhaled and biopharmaceutical projects,” Bowen said.
Waters also unveiled three new solutions with UNIFI: the Waters Screening Platform Solution, the Waters Pesticide Screening Application Solution and the Waters Metabolite Identification Application Solution. These new solutions with UNIFI bring everything a laboratory needs – LC and MS hardware, software, consumables and standards and reagents – for routine, general purpose screening, for screening of pesticide residues in foods and beverages and for the separation, identification, and quantification of metabolites.
For advancing scientific research, Waters has announced new software that promises to revolutionise the way results are visualised and processed for ion mobility mass spectrometry experiments.
Brian Smith, Vice President, Mass Spectrometry Operations, Waters Division said, “Mass spectrometry is the backbone of today’s analytical laboratory. As it becomes ever more prevalent and a workhorse technique, scientists expect more from it. Waters is responding by introducing innovations at both ends of the analytical spectrum – from research to everyday analysis. With the innovations we are announcing today, we are opening up new paths for discovery and putting laboratories on a path to more accurate and faster results.”
With the introduction Waters Xevo G2-S QTof and Waters Xevo G2-S Tof Mass Spectrometers, Waters is bringing the novel StepWave ion optics technology to its benchtop time-of-flight mass spectrometers. Waters StepWave ion optics technology maximises instrument sensitivity while minimiming routine maintenance. It transfers ions from the ion source with the highest possible efficiency while actively filtering out undesirable neutral contaminants. As a result MS signals are dramatically increased and, because critical components in the device stay clean for longer periods of time, quantitative results are more reproducible and laboratories experience less downtime due to routine cleaning and maintenance.
Previously available before on only the benchtop Waters Xevo TQ-S (tandem quadrupole) mass spectrometer and Waters SYNAPT G2-S HDMS mass spectrometers, StepWave brings a new level of performance to the Xevo quadrupole time of flight and time of flight instruments delivering superior UPLC-compatible mass resolution, matrix-tolerant dynamic range, quantitative performance, mass accuracy and speed of analysis – simultaneously.
EP News Bureau — Mumbai
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